Name: ARLON BASTOS DA ROSA
Publication date: 19/10/2011
Examining board:
Name |
Role |
|---|---|
| MARCELO BARRETO DA SILVA | Internal Examiner * |
Summary: ROSA, Arlon Bastos da, M.Sc., Universidade Federal do Espírito Santo, October 2011, Chemical and biological study of maleic anhydride aminoderivados; Advisor: Prof. Dr. Valdenir Jose Belinelo, Co-supervisor: Prof. Dr. Marcelo Barreto da Silva.
The search for new substances against microorganisms and weed control, they become increasingly resistant to those used, generated the need to know and search for new chemical entities. So were synthesized N-alkyl derivatives Maleamic Acid, by reacting Maleic Anhydride with various amines. The products were tested against bacteria, pathogenic fungi and also evaluated the regulatory effect of seed germination and plant growth. Of chemical entities synthesized also determined the minimum inhibitory concentration (MIC), the dilution technique in 96-well microplates. Antibacterial activity was not observed for the strains Escherichia coli ATCC 8739, Staphylococcus aureus ATCC 25923, Staphylococcus aureus hospital and Bacillus cereus ATCC 11778. In tests with phytopathogenic fungi Colletotrichum musae Fusariun solani f. sp phaseoli, Fusariun solani f. sp piperis Alb. and Penicillium sp, substances synthesized from Aniline, Ethylamine, Piperazine and Phenylhydrazine showed antifungal properties, enabling the development of fungicides for agricultural use. In the experiments to verify the effect on plant development Sorghum bicolor L. (Sorghum), Cucumis sativus L. (Cucumber), Lactuca sativa L. (Lettuce) and Bidens pilosa L. (Black cock), the F-test analysis of variance showed significant results in the parameters of development of roots and aerial parts of all plants tested. Analysis of variance revealed for Lactuca sativa L., a significant effect between treatment means
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for the variable percentage of germination by the use of
Maleic Anhydride and derivatives of Aniline, Cyclohexylamine, Ethylenediamine, Phenylhydrazine and Piperazine. The gradients of the germination speed index and development of the seedling of Lactuca sativa L. were significant for all substances except Ethylamine and Piperazine, respectively. Except for the starting reagent Maleic Anhydride, the variation of root length was significant for Lactuca sativa L. for all eight synthetic substances. Therefore, from the results obtained during the development and implementation of the project, it is concluded that the synthesis of substances remains an ally in the development of new products and/or improving existing ones, requiring more in-depth and ongoing studies for the improving techniques employed.
